The Faculteit Geneeskunde en Farmacie, Department Basis (bio)-medische wetenschappen, is looking for a predoctoral researcher.
More concretely your work package contains:
The Movahedi lab at the Vrije Universiteit Brussel is looking for a bioinformatician or computer scientist to join our team. You will play a key role in our ambition to develop new treatment paradigms for neurodegenerative diseases of the brain. By relying on innovative technologies, we aim to understand how immune cells modulate brain disorders and how they can be engineered to ameliorate disease. Our research heavily draws on single-cell omics profiling and gene editing technologies, for which bioinformaticians and AI specialists are essential. Your responsibility will be to implement and develop analysis pipelines for these state-of-the-art methodologies. This will include single-cell multiomic spatial profiling and CRISPR-sequencing. You will further implement algorithms that offer predictions on putative biological functions, cell-cell interactions, cellular differentiation trajectories and the gene regulatory networks that drive cellular identity and activation.
Our lab is located at the university medical campus of the Vrije Universiteit Brussel (Jette campus), in the hearth of Europe. You will join a dynamic and ambitious team of highly motivated international scientists, in a friendly environment where you can thrive both at a professional and personal level. Long-term career opportunities and mentoring are part of the package.
Funding is available via the ERC consolidator grant ReplaceMi. We offer an initial full-time 2-year position that can be renewed.
Relevant publications of our lab
De Vlaminck et al. Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation. Immunity 2022. PMID: 36228615
Scheyltjens et al. Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues. Nature Protocols 2022. PMID: 35931780
Lodder et al. CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia. Acta Neuropath Comm 2021. PMID: 34103079
Pombo Antunes et al. Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization. Nature Neuroscience 2021. PMID: 33782623
Van Hove H et al. A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. Nature Neuroscience 2019. PMID: 31061494
www.brainimmuneatlas.org
For this function, our Brussels Health Campus (Jette) will serve as your home base.
Similar Positions
-
Infering Plasticity Mechanisms In Cancer Cell Population, phlam laboratory, France, 25 days ago
24 Mar 2024 Job Information Organisation/Company phlam laboratory Research Field Computer science Researcher Profile First Stage Researcher (R1) Country France Application Deadline 30 Jun 2024 - 2...
-
Postdoc/Assistant Professor , Institute of Fundamental Technological Research Polish Academy of Sciences, Poland, 9 days ago
10 Apr 2024 Job Information Organisation/Company Institute of Fundamental Technological Research Polish Academy of Sciences Department Department of Biosystems and Soft Matter Research Field Biolo...
-
Research Assistent: Exploring The Role Of Cell Size On Aging Of Human Hematopoietic Stem Cells, Karolinska Institutet, Sweden, about 17 hours ago
Do you want to contribute to top quality medical research? The failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despi...
-
Assistant Professor, Warsaw University of Technology, Poland, 27 days ago
22 Mar 2024 Job Information Organisation/Company Warsaw University of Technology Research Field Biological sciences » Biology Chemistry » Analytical chemistry Chemistry » Instrumental analysis Res...
-
Research Laboratory Technician Position In Diabetes/Immunometabolism Lab, University of Basel, Switzerland, 28 days ago
22 Mar 2024 Job Information Organisation/Company University of Basel Research Field Chemistry » Biochemistry Medical sciences » Other Researcher Profile First Stage Researcher (R1) Country Switzer...
-
Bioinformatician, VIB, Belgium, about 11 hours ago
Position summary Applications are invited to join an exciting research program within the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) led by the two directors D Lambrechts and JC M...