The Department of Pharmaceutical Sciences invites applications for a postdoc position. The candidate should have an excellent track record in cell biology/biotechnology to conduct current research projects
Until today there is no approved nanomedicine marketed that specifically targets a defined cell subsets to deliver therapeutics. However, in the advent of mRNA technology revolutionizing how patients can be treated in the future, the tremendous impact on human health originating from defined delivery of drugs becomes even more apparent. In this project, the successful applicant will be involved in a three-year mission driven by the development of small molecule-based targeted delivery systems for cell specific targeting. For that, small molecules exposed on nanoparticles are employed for active targeting of receptors present on the targeted cells. Hence, the concept of targeted delivery should be familiar to the applicant. The successful applicant should be familiar with aseptic cell culture techniques, culturing primary cells, design of cell-based assays using flow cytometry and standard imaging techniques. It is a plus if you bring in knowledge on planning and conducting basic animal experiments, histology, formulation of lipid-based nanoparticles and background in bioinformatics using common databases and simple programming to analyze larger datasets.The applicant should also have good project- and time management skills and keep a very good documentation of the work. Until today there is no approved nanomedicine marketed that specifically targets a defined cell subsets to deliver therapeutics. However, in the advent of mRNA technology revolutionizing how patients can be treated in the future, the tremendous impact on human health originating from defined delivery of drugs becomes even more apparent. In this project, the successful applicant will be involved in a three-year mission driven by the development of small molecule-based targeted delivery systems for cell specific targeting. For that, small molecules exposed on nanoparticles are employed for active targeting of receptors present on the targeted cells. Hence, the concept of targeted delivery should be familiar to the applicant. The successful applicant should be familiar with aseptic cell culture techniques, culturing primary cells, design of cell-based assays using flow cytometry and standard imaging techniques. It is a plus if you bring in knowledge on planning and conducting basic animal experiments, histology, formulation of lipid-based nanoparticles and background in bioinformatics using common databases and simple programming to analyze larger datasets.The applicant should also have good project- and time management skills and keep a very good documentation of the work.
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