Post-Doc Position in lung cancer research
Our research team focus in the understanding of the signalling pathways underlying KRAS and EGFR driven lung adenocarcinoma, with a strong interest in the translational aspects. We make use of mouse genetic technology (conditional knock-outs, knock-ins, CRISPR/Cas9, etc.), (xeno)graft models, cell culture, drug treatments, human patient samples and bioinformatics to explore different aspects of lung cancer
The successful candidate will investigate the role of glucocorticoid receptors in KRAS and EGFR driven lung adenocarcinoma using genetically engineered mouse models.
We offer to you:
A full time contract for 1.5 years. Post-doc salary accordingly to FWF standards (4,061.50 Euros per month, gross salary)
A multidisciplinary team consisting of biochemists, molecular and cell biologists and medical doctors.
“State of the art” research facilities
We expect from you:
Extensive experience in the field of (lung) cancer, genetic mouse models, oncoimmunology and bioinformatics
Planning and executing in vitro and in vivo experiments involving mouse cancer studies.
Managing and developing research projects independently
Managing collaborative projects within our research group and with our collaboration partners.
Applying for third party money.
Selected publications of the group:
Caratti, B. et al., 2022. The glucocorticoid receptor associates with RAS complexes to inhibit cell proliferation and tumor growth. Science Signaling.
Breitenecker, K. et al., 2021. Downregulation of A20 promotes immune escape of lung adenocarcinomas. Science Translational Medicine.
Mohrherr, J. et al., 2019. JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression. International Journal of Cancer.
Moll, H.P. et al., 2018. Afatinib restrains K-RAS-driven lung tumorigenesis. Science Translational Medicine.
Grabner, B. et al., 2015. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nature Communications.
Musteanu, M. et al., 2012. A mouse model to identify cooperating signaling pathways in cancer. Nature Methods.
The position is available as soon as possible. Applicants should submit: A cover letter (explaining their motivation and experience), CV and names and contact details of 2 referees. Short listed candidates will be notified and invited for interview.
Deadline 21st of September 2022
Applications should be addressed to:
Emilio Casanova
Medical University of Vienna
Center for Physiology and Pharmacology
Institute of Physiology
Währinger Str. 13a
A-1090 Vienna,
Austria
Phone: 43 1 40160 31341
Email: [email protected]
https://emiliocasanova.wixsite.com/casanova-lab
https://scholar.google.at/citations?user=2RnYZfQAAAAJ&hl=en
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