LABORATORY TECHNICIAN FOR HIGH-THROUGHPUT TRANSLATIONAL EPIGENETICS LABORATORY

The European Translational Oncology Prevention and Screening Institute (EUTOPS) is a new research institute at the University of Innsbruck, supported by the Land Tirol and led by Prof. Martin Widschwendter, who also holds a professorship at University College London and a guest professorship at the Karolinska Institutet in Stockholm. Our research focus is to identify and validate epigenetic signatures for individualised prevention, risk prediction, and early detection of cancer in line with the principles of P4 medicine (predictive, preventive, personalised and participatory). Within this context, our work focuses on DNA methylation-based risk prediction and monitoring of cancer preventive measures in a translational setting, applying high throughput methodologies in international clinical trials and population-based studies.

We have established a new high-throughput translational epigenetics and genetics laboratory and are looking for a molecular biology laboratory technician, preferably with working experience in the automation and high-throughput field. The University of Innsbruck’s newly established translational epigenetics laboratory is located in close proximity to a large pathology/cytology/molecular laboratory and sited in Zams, 50 minutes west of Innsbruck close to several famous ski resorts (e.g. St. Anton, Lech, Pitztal, and Sölden) allowing for ample leisure activities in winter and summer yet within a short distance of major European cities such as Innsbruck, Munich, Zurich, and Verona.

The role and what will make you an ideal candidate

You will join an interdisciplinary, international, and highly motivated team with expertise in epigenetics, clinical research, biostatistics and oncology. You will be responsible for the day-to-day operation of our high-throughput epigenetics (and genetics) sample processing, will support with the establishment and maintenance of automated workflows, and will communicate regularly with the team.

This role will be an excellent opportunity for a scientist or laboratory technician with expertise in high-throughput and automation technologies. We highly value team members capable of working independently with a sense of self-initiative and “can do” attitude.

Your tasks and responsibilities:

• Operation of automated high-throughput workflows for
  • • DNA extraction and modification (bisulfite conversion, restriction, etc.),
    • Microarray (mainly IlluminaEPIC array),
    • RT-qPCR (e.g., MethyLight),
    • NGS library preparation using automated liquid handling platforms such as Tecan, Hamilton or EpMotion.
• Troubleshooting and optimisation of the automation pipelines.
• Ensuring compliance with all internal and external policies as well as health and safety guidelines.
• Regular communication with other members of the institute, providing updates on progress, areas of improvement or risks.
• Prioritize tasks in line with short- and long-term needs of the research group.