Undertake investigations looking at the impact of the interaction between genetic/epigenetic factors and lifestyle factors (namely sleep, physical activity and diet, including metabolic factors, eg. Insulin Resistance) on both the risk for developing Alzheimer's Disease (AD) and related clinical (memory performance) and imaging (atrophy and brain beta-amyloid burden). Understanding the gene-lifestyle interactions can help ascertain what genetic factors underpin lifestyle associations as well as providing the initial steps towards individualised implementation of lifestyle interventions. Multiple a priori genetic candidates have been chosen for each research area, based on prior evidence with respect to the lifestyle area of choice as well as unbiased discovery-based approaches that will utilise large publically available datasets.
These studies will leverage extensive existing genetic (genome wide SNP and next generation sequencing), epigenetic (genome wide methylation) and longitudinal data from the Australian Imaging, Biomarker and Lifestyle (AIBL) study of Ageing. We have multiple projects on offer across many of the aforementioned lifestyle areas.
Collaboration: This project involves collaboration with the Australian Imaging, Biomarker and Lifestyle (AIBL) study of Ageing participating research organisations of which ECU is one.
Desired Skills: This project is predominantly utilizing extensive existing data. Whilst there will be within project skills development background skills and knowledge in data analysis is highly desirable.
Project Area: Medical Science (Neuroscience/Genomics)
School / Research Centre / Institute: Centre for Precision Health
Project level: Masters, PhD
Funding: Applicant should apply for ECUHDR or RTP Scholarship
Start Date: Ongoing
Senior Data Scientist, Curtin University, Australia, 2 days ago
Job Reference: 892508 The Curtin Institute for Computation (CIC) Computation now fundamentally underpins the majority of internationally competitive research across all fields and disciplines. As ...
Chair Country Health Research And Innovation, Curtin University, Australia, about 20 hours ago
Job Reference: 824525 Your new role The position is an opportunity for an outstanding leader to play a key role in transforming the health environment in regional, rural and remote Western Austral...
Administrative Support Officer, Curtin University, Australia, about 20 hours ago
Job Reference: 891981 About us The Act Belong Commit campaign managed by Curtin-based Mentally Healthy WA, is funded by Healthway and the Mental Health Commission, and is a community-based mental...
Counsellor/Counsellor (Registrar), Curtin University, Australia, 5 days ago
Job Reference: 856884 About us Curtin University is ranked in the top 1% of universities worldwide (ARWU 2018 and QS World University Rankings 2019), and is placed 20th in the world for universiti...
Lecturer, Curtin University, Australia, about 20 hours ago
Job Reference: 913643 About us The Faculty of Health Sciences follows a long tradition of discipline-based course delivery in the health professions. Courses in the Faculty provide a hands-on app...
Lecturer Public Relations, Curtin University, Australia, 7 days ago
Job Reference: 877743 About us The School of Marketing and Management is home to leading research entities such as the Future of Work Institute, the John Curtin Institute of Public Policy, the Lux...