Undertake investigations looking at the impact of the interaction between genetic/epigenetic factors and lifestyle factors (namely sleep, physical activity and diet, including metabolic factors, eg. Insulin Resistance) on both the risk for developing Alzheimer's Disease (AD) and related clinical (memory performance) and imaging (atrophy and brain beta-amyloid burden). Understanding the gene-lifestyle interactions can help ascertain what genetic factors underpin lifestyle associations as well as providing the initial steps towards individualised implementation of lifestyle interventions. Multiple a priori genetic candidates have been chosen for each research area, based on prior evidence with respect to the lifestyle area of choice as well as unbiased discovery-based approaches that will utilise large publically available datasets.
These studies will leverage extensive existing genetic (genome wide SNP and next generation sequencing), epigenetic (genome wide methylation) and longitudinal data from the Australian Imaging, Biomarker and Lifestyle (AIBL) study of Ageing. We have multiple projects on offer across many of the aforementioned lifestyle areas.
Collaboration: This project involves collaboration with the Australian Imaging, Biomarker and Lifestyle (AIBL) study of Ageing participating research organisations of which ECU is one.
Desired Skills: This project is predominantly utilizing extensive existing data. Whilst there will be within project skills development background skills and knowledge in data analysis is highly desirable.
Project Area: Medical Science (Neuroscience/Genomics)
School / Research Centre / Institute: Centre for Precision Health
Project level: Masters, PhD
Funding: Applicant should apply for ECUHDR or RTP Scholarship
Start Date: Ongoing
Chair Ophthalmic Big Data, Curtin University, Australia, about 10 hours ago
Job Reference: 824862 Your new role The Chair will have responsibility for enhancing leadership and research to further the reputations of both Curtin and Lions Eye Institute in areas such as the ...
Senior Health & Safety Advisor, Curtin University, Australia, 2 days ago
Job Reference: 811437 SENIOR HEALTH AND SAFETY ADVISOR About Us Health and Safety Department Curtin University’s team of health and safety professionals provide advice and assistance in the implem...
Chair Country Health Research And Innovation, Curtin University, Australia, about 10 hours ago
Job Reference: 824525 Your new role The position is an opportunity for an outstanding leader to play a key role in transforming the health environment in regional, rural and remote Western Austral...
Lecturer, Curtin University, Australia, 11 days ago
Job Reference: 802029 “Curtin University considers that being Aboriginal or a Torres Strait Islander is a genuine occupational requirement for this position under section 50D of the Equal Opportun...
Associate Lecturer, Curtin University, Australia, 11 days ago
Job Reference: 802027 “Curtin University considers that being Aboriginal or a Torres Strait Islander is a genuine occupational requirement for this position under section 50D of the Equal Opportun...
Project Coordinator, Curtin University, Australia, 6 days ago
Job Reference: 819014 1x 24-month fixed term contract – full time 1 x 18-months fixed term contract – full time 1 x 12-month fixed term contract – full time $92,457 - $99,271 + 17% Superannuation ...