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Field
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) bioinformatic analysis of single-cell genomics datasets, (c) a translational approach using blood or tissue samples from humans, (d) wet-lab methods in virology (such as sterile cell culture in an enhanced
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cells, pericytes) to construct complex 3D assembloids and organ-on-a-chip platforms. • Mechanistic Dissection: Deploy CRISPR/Cas9 genome editing, shRNA/ASO tools, and pharmacological screens
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other samples, as well as the UK Biobank, AllOfUs, etc; (b) Psychiatric Genomics Consortium projects focusing on substance use disorder genetics but also including depression and anxiety genetics and
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pathways that regulate hematopoiesis. Our current research focuses are: 1) Study of epigenetic modulation in hematopoietic stem cell differentiation using genome wide and single cell RNA seq analysis; 2
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to extract biological information from high-dimensional data Integrate proteomics data with biological (e.g. genomics) data and clinical information Collaborate closely with mass spectrometry experts
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. multidimensional data (phenomic, genomic, weather data) for biological discovery and prediction. -Analyzes research data and summarizes results. -Writes and contributes to research papers, articles, and publications
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-derived cells and single-cell perturb sequencing to establish foundational models to predict the effects of potential drug candidates on cardiovascular diseases. By combining genome engineering, functional
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microbial genetics, genomics, or synthetic biology. Strong understanding of the cyanobacterial circadian clock system, including the KaiABC oscillator and downstream signaling and transcriptional pathways
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program. Our work focuses on the development of advanced cancer models, integrative genomic analyses, and the discovery of novel therapeutic strategies. Using systematic, interdisciplinary approaches
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Columbia Center for Translational Immunoogy | New York City, New York | United States | about 14 hours ago
. Experimental approaches will include primary human cell culture, ELISA, ELISPOT, protein assays, RNA-seq, single-cell genomic approaches, and functional cell-based assays. The applicant will also be involved in