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new modeling approaches for coupling functional genomics techniques with computational analyses to understand gene regulation in health and disease. Such models are based on multi-omics high
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bioinformatics, bioinorganic chemistry, structural biology, microbial genomics, biogeochemistry, molecular evolution, and synthetic organic chemistry that will allow the design of interdisciplinary
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genomics, molecular biology, and tumor immunology underlying rare hematological neoplasms and aberrant cell signaling. Utilizing multi-omics, mouse models (GEMMs/PDXs), and human biospecimens, the
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