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that HbA1c can sometimes lead to incorrect management of diabetes. To address this problem, the project will use statistical genetics to untangle these distinct biological pathways. By separating the genetic
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to evaluate and advance machine learning algorithms for one of the following application areas: “Characterising forests variations in relation to distance from pre-Columbian earthworks in the Amazon forest
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genetics to understand the complex relationships between severe mental illness, inflammation, and obesity and other adverse metabolic health outcomes. This research is important as people with severe mental
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healthy despite being at high genetic risk of dementia? This project will use cutting-edge genetic and molecular data from large human biobanks to identify molecular factors that help protect against
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cognition simulation algorithms, benchmark evaluations against direct behaviour-to-label baselines, interpretable markers of cognitive-affective dysfunction, and prototypes for non-invasive mental health
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sequence the complete DNA of babies at birth to screen for hundreds of genetic conditions. This PhD project will generate the evidence to inform which genes and variants should be included in newborn genome
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number of genetic mutations in Schizophrenia patients called “rare coding variants.” These mutations change the proteins they produce, but for many of them, we do not yet know the functional consequences
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appears protective. This inverse relationship provides a powerful genetic entry point to identify pathways that drive vulnerability or resilience genome wide. This project will use computational methods
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problem to improve the clinical pathway for individuals who are at risk of dementia due to well-established risks such as cognitive decline, lifestyle, medical or genetic factors. This project aims
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. The successful applicant will work with experts in diabetes, data science, and genetics, and use detailed existing studies of hundreds of thousands of people with diabetes, to understand what is causing apparent