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sequence the complete DNA of babies at birth to screen for hundreds of genetic conditions. This PhD project will generate the evidence to inform which genes and variants should be included in newborn genome
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repetitive DNA is impossible to resolve using conventional short-read sequencing technologies. Your role will facilitate the identification of novel genetic variation in poorly explored genomic regions, and in
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investigate the influence of trajectory accuracy on player perception and engagement within a dedicated laboratory environment. Developing distributed synchronization algorithms: we will design and implement a
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Mitochondrial diseases are among the most common inherited metabolic disorders. Despite advances in genetic diagnosis, important questions remain regarding the processes that drive disease progression and
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. The success of neural networks as a platform for developing AI is partially explained by the fact that backpropagation, the primary algorithm used to train them, runs efficiently on conventional CMOS hardware
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number of genetic mutations in Schizophrenia patients called “rare coding variants.” These mutations change the proteins they produce, but for many of them, we do not yet know the functional consequences
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appears protective. This inverse relationship provides a powerful genetic entry point to identify pathways that drive vulnerability or resilience genome wide. This project will use computational methods
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problem to improve the clinical pathway for individuals who are at risk of dementia due to well-established risks such as cognitive decline, lifestyle, medical or genetic factors. This project aims
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. The successful applicant will work with experts in diabetes, data science, and genetics, and use detailed existing studies of hundreds of thousands of people with diabetes, to understand what is causing apparent
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-class or upper second-class honours undergraduate degree, a Master’s degree and/or relevant research experience in areas including biochemistry, molecular biology, genetics and bioinformatics. Skills and