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Dr. Vincenzo Calvanese. RESEARCH DESCRIPTION Hematopoietic stem cells (HSC) are a life-saving therapy for leukemia, and have found broadened applications in gene and cell therapy against other cancers
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understand the pathogenesis of inflammatory bowel disease (IBD) and developing gene editing therapies for IBD. The role will include working with IBD patient-derived organoids, advancing human in vitro assays
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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signaling, and GPCR or kinase biology is essential. Experience in at least two of the following—mammalian cell culture and iPSC differentiation, site-specific genome integration and CRISPR/Cas9 gene editing
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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signaling, immunology, or host‑pathogen interactions. Experience with in vivo mouse models and mammalian cell culture. Proficiency in molecular biology techniques (cloning, qPCR, Western blotting, gene
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functional analyses of the genetic drivers of Inflammatory Bowel Disease.” Job Duties Primary Research Activities: Designs and executes high-throughput RNAi screens of IBD risk genes in C. elegans. Performs
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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specializes in precision cardiovascular medicine, leveraging cutting-edge approaches such as human iPSC-derived 2D cardiovascular cells, 3D vascularized cardioids, CRISPR gene editing, high-throughput CRISPRko