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and functionally distinct macrophage subpopulations (Coates et al., 2021 eLife). How these relate to our own macrophage subpopulations remains a key gap in our understanding, while we have little
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Pluripotency and Differentiation . LncRNAs are an exciting class of of RNA molecules among which very few have thus far been functionally characterized in depth. We performed an RNA-seq screen in
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shaping techniques (e.g., using graded filters) to minimize diffraction artifacts and improve beam transportability Develop an intelligent, AI/Reinforcement Learning-based system to automatically
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single-cell DNA methylation and transcriptomic libraries, and functionally evaluate therapies targeting resistant states using cell and organoid models. As the first postdoctoral researcher in the
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findings in peer-reviewed journals. Experience investigating and characterizing natural products biosynthesis or experience purifying and functionally characterizing oxygen-sensitive enzymes (for example
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-quadruplexes (G4) and i-motifs (iM) are paradigmatic non-canonical nucleic acid structures that are abundant in the human genome and overrepresented in evolutionarily conserved and functionally important
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Objectives : In this role, you will focus on Dendritic cells (DCs)—the sentinels of the immune system—which are developmentally and functionally heterogeneous. Your primary objectives will be: Better
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 7 days ago
, structural biology, biochemistry and medicinal chemistry, the new postdoc will have the opportunity to work on unprecedented simulations and AI-driven drug discovery of functionally important
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libraries to profile the binding of complex mixtures of antibodies Interact and collaborate with scientists cross-functionally, gaining broad exposure to the process of drug discovery Make novel
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 20 hours ago
remodel the cellular proteome to drive oncogenic transformation? How are RBPs functionally repurposed as cells transition from a healthy to malignant state? How do RNA binding proteins coordinate