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the following areas: -Biophysical instrumentation development: optical and mechanical design, simulation, development and control -Optical imaging; Single-molecule fluorescence and FRET ; Lasers
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droplets, and allosteric coupling, to exquisitely control signal routing. We integrate structural biology (NMR, X-ray, cryoEM) and biophysical techniques (FRET, ITC, BLI) with cellular readouts (TopFlash
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techniques (FRET, ITC, BLI) with cellular readouts (TopFlash, BRET) and proteomics to understand DVL structure, function, and regulation. Candidates can choose among three open questions, that if
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isolation and culture of mouse cells from various organs Basic skills in biochemistry (e.g. protein identification, IC50 binding assays, fluorescence techniques such as TRF, FRET, HTRF). Applicable