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for an energetic and creative individual to help discover and characterize functional RNA elements within the human virome, the trillions of viruses that reside in the human body. This project builds on our recent
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to the discovery of dozens of classes of bacterial riboswitches and other structured noncoding RNAs. We are now applying similar genome-scale discovery methods to identify functional RNA regulatory elements in
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research Strong quantitative skills, including experience with regression, structural equation modeling (SEM), and multilevel modeling (MLM) Experience with measurement development, factor analytic methods
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. This interdisciplinary project builds on the laboratory’s recent discovery of the first riboswitch candidates in humans and other mammals. The successful candidate will help investigate how these RNA elements function in
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well as part of an ENCODE functional characterization center. The lab is especially interested in non-coding cis-regulatory elements (CREs) and the variation within them, using high-throughput experimental
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) consortium as well as part of an ENCODE functional characterization center. The lab is especially interested in non-coding cis-regulatory elements (CREs) and the variation within them, using high-throughput