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, HBV, HCV, and alcohol-induced liver injury • exosomes in therapeutic delivery and pathogenesis • long-acting antiviral and immunomodulating drug development • studies of innate and adaptive immunity
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cancers. The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies. The role of extracellular vesicles/exosomes in cancer pathogenesis and their
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Regenerative medicine is the heart of what we do at ICR, with many parts centered on induced pluripotent stem (iPS) cells, iPS cell-derived stem cells, and their products (e.g. exosomes). We
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programs that can complement the clinical interests and ongoing research of the department. Current faculty have active research programs on non-coding RNA, exosome biology, metastasis and therapeutics in
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, S.; Caputo, F.; Urban, P.; Maguire, C. M.; Bremer-Hoffmann, S.; Prina-Mello, A.; Calzolai, L.; Mehn, D. Nanomedicine-Uk 2018, 13, 539-554. Drug delivery; Drug product; Drug release; Exosomes; In vitro
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. 15(22): p. 2149-2170. production; characterization; drug delivery; exosomes; extracellular vesicles; gene delivery; purification; measurement assurance; method development; reference materials