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to generate all the cells in the organism. The formation of a totipotent cell entails epigenetic reprogramming and major large-scale chromatin organisation and transcriptional changes. A hallmark of this
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Germany | 3 months ago
entails epigenetic reprogramming and major large-scale chromatin organisation and transcriptional changes. A hallmark of this process is the activation of repetitive elements and transposable elements
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preclinical models to define disease-associated metabolic and epigenetic programs that control stem cell development, and how these processes go awry in cancer progression. Our lab is equipped with cutting-edge
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for Pathology M. Rose: Neuronal Diversity, Omics, and Imaging in Brain Development and Disease H. Park: Breast cancer, epigenetics, environmental exposures, and biomarkers F. Rahmatpanah: Prostate cancer
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of epigenetics of psychiatric traits; and studies of whole genome sequence in psychiatric traits. A NIDA-funded study concentrates on cannabis use genetics and PRS prediction of response to THC in a laboratory
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and metabolic stress signaling in cancer metastasis. Our goal is to reveal how the mitochondrial metabolism and nutrient stress controls metastatic progression through epigenetic remodeling
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RNA metabolism in iPSC models of ALS/FTD. Carry out NextGen sequencing experiments and data analysis to determine epigenetic and transcriptomics changes in iPSC models of ALS/FTD. Carry out experiments
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leaves durable epigenetic and transcriptional scars that shape long term immunity, inflammation, and lung repair. This position is ideal for scientists excited to combine single cell transcriptomics and
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The dos Santos Laboratory is seeking highly motivated postdoctoral fellows to join a dynamic and collaborative research program focused on defining epigenetic and non-genetic determinants of breast
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is a strong asset. Knowledge and training experience in cancer biology and/or epigenetics is a strong asset. Good capabilities to work independently and to lead a project. Good collaborative skills and