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models. Current treatment strategies for HBV are life-long and rarely curative. Finite antiviral and immunomodulatory therapeutic strategies are being pursued for an HBV functional cure to treat the 254
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of peptidoglycan, mass spectrometry, cellular and animal models, and in confocal/immunofluorescent microscopy. The postdoc will study the model organism Helicobacter pylori and its mechanisms of release of immune
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of computational biology, protein language models, structural biology, and immunology. 🎯 Main Missions Build and curate large-scale antigen sequence datasets for training and fine-tuning protein language models
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-learning model. Expected outputs include parameter priors, benchmarking results, a simulation pipeline, curated synthetic datasets, and Bayes optimal errors. Publication / conference: Depending on progress
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A post-doctoral position is available to advance the development of a 3D human lymphoid organ model and apply this model to test new mRNA vaccination platforms. The position is fully funded for 2.5
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, the causative agent of leptospirosis, offers an excellent model for studying the mechanisms underlying host adaptation and zoonotic emergence. Virtually all mammalian species can act as reservoirs
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immunotherapy interventions targeting CD4+ T cells based on recombinant monoclonal antibodies or mRNA-containing lipid nanoparticles. The project will be primarily developed in a pre-clinical murine model of lung
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dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional
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models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics, spatial transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using