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carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins
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, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins that represent the majority of all current drug targets
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across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across
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to economic and environmental benefits. Despite the growing impact of biocatalysis in industrial chemistry, the full potential of this technology is yet to be unlocked. Important current limitations
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benefits. Despite the growing impact of biocatalysis in industrial chemistry, the full potential of this technology is yet to be unlocked. Important current limitations are the following: i) only a limited
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funded for four years by the recently awarded ERC Starting grant ‘ReCNNSTRCT’. Biocatalysis uses enzymes to replace traditional catalysts. This technology has already established sustainable enzymatic
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to diagnose and treat. Intestinal tissue is easy to access with nanoparticles, which offers excellent opportunities for therapy and diagnosis e.g. a theranostic approach. The current proposal aims to find (I
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excellent opportunities for therapy and diagnosis e.g. a theranostic approach. The current proposal aims to find (I) relevant target receptors in diseased intestinal tissue, with special focus on macrophages
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fundamental challenge is that current reservoir modelling workflows almost always underestimate geological heterogeneity and hence provide unrealistic uncertainty bounds. The unique database of the Groningen
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, because reservoir models are used to investigate how geological heterogeneities impact production rates and production risks. A fundamental challenge is that current reservoir modelling workflows almost