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Max Planck Institute of Molecular Physiology, Dortmund | Dortmund, Nordrhein Westfalen | Germany | about 1 month ago
biological pathways underlying the assembly of multimeric membrane proteins using CRISPR-based genetic screens, as well as mechanistic dissection using techniques from molecular biology, cell biology
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-learning approaches. Projects may also include detailed molecular and functional characterization of particularly exciting candidate evolutionary changes using organoid and mouse models, CRISPR-based
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. Mutations and deletions of NR2F1 lead to Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Using neuronal cells derived from CRISPR/Cas9 engineered human induced pluripotent stem cells (hiPSC) we model
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-on experience in molecular biology and biochemistry including protein, RNA and DNA isolation from tissues and CRISPR-Cas9 cell generation is required. Full command of English, written and spoken. Track-record
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Germany | 3 months ago
biology and organismal biology, including animal models is essential. Previous hands-on experience in molecular biology and biochemistry including protein, RNA and DNA isolation from tissues and CRISPR-Cas9
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German Cancer Research Center in the Helmholtz Association (DKFZ) | Oettingen in Bayern, Bayern | Germany | 3 months ago
. Nature. 2026 Feb 25. doi: 10.1038/s41586-026-10187-2. By developing and applying genetic technologies for high-throughput applications in cells and mice, including CRISPR or transposon tools for massively