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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | 19 days ago
therapeutic use. However, traditional medicinal chemistry often restricts itself to low structural complexity molecules that cover only a small portion of the theoretically accessible chemical space. This
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systems. 3. Structural characterization of selected complex/micelle systems. This will be accomplished by NMR, including 19F spectra for Cu(II) complexes and isostructural Cu(II) replacements with
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activity in vitro; basic knowledge of bioinformatics, molecular modelling and docking and/or structural analysis of protein–ligand complexes, as well as the ability to use in silico results to guide
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 2 months ago
CtBP-mediated transcriptional repression and reorganizes transcriptional corepressor complexes. By integrating molecular biology, cell biology, quantitative microscopy, biochemistry, proteomics, and