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focus on mutational processes that drive rapid genome evolution, such as the chromosome “shredding” phenomenon called chromothripsis which is characterized by extensive breakage and rearrangements on a
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, including advanced microscopy, transgenic animal services, embryo manipulation platforms and integrated single-cell genomics. You will work alongside researchers studying chromosome biology, developmental
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that drive rapid genome evolution, such as the chromosome “shredding” phenomenon called chromothripsis which is characterized by extensive breakage and rearrangements on a small number of chromosomes
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-nucleus multiomics, CUT&RUN and low-input chromosome conformation capture techniques. You will be based at the MRC Laboratory of Medical Sciences; a discovery research institute located at Imperial