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for an energetic and creative individual to help discover and characterize functional RNA elements within the human virome, the trillions of viruses that reside in the human body. This project builds on our recent
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pluripotent stem cells and iPSCs. Differentiation of stem cells into neural cell types and development of three-dimensional brain organoid models. Functional characterization of neural activity in neural
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collaborators, who contribute clinical trial samples for ongoing exosome studies. The PI also co-directs the National Multiple Sclerosis Brain Bank, which provides unique access to well-characterized postmortem
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of patient-derived xenograft (PDX) models. Molecular and cellular biology approaches, including cloning, plasmid preparation, gene editing, and functional characterization of cellular phenotypes. Execution
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constructs and within-person change, as well as spoken narrative data. The overarching goal is to characterize longitudinal trajectories of core computational constructs (e.g., reward learning, decision-making
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Postdoctoral Associate | Mitochondrial Genomics | Lake Lab — Yale University, Department of Genetics
our research please see our website: https://www.thelakelab.org/ Responsibilities Generate and characterize novel cellular models of mitochondrial genome dysfunction using genome-editing and related
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Templeton Foundation. The project seeks to discover and characterize novel RNA-based gene regulatory mechanisms in mammals, with a particular focus on riboswitches that sense lithium and sodium ions
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well as part of an ENCODE functional characterization center. The lab is especially interested in non-coding cis-regulatory elements (CREs) and the variation within them, using high-throughput experimental
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blotting, immunoprecipitation (IP), and co-immunoprecipitation (co-IP) Generate, maintain, and characterize blood vessel organoids, including bioprinted vascular models Maintanance and phenotype zebrafish
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characterization of mammalian riboswitches. This position, supported by a grant from the John Templeton Foundation offers an exciting opportunity to help uncover previously unknown RNA-based genetic regulatory