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Field
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cell phones and dedicated recording devices, are also growing in scale, creating the potential to complement, extend, and expand human observations. However, a key challenge is translating imperfect
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multidisciplinary bioimaging programme, 3DxN. Background Ageing and disease are accompanied by changes in the appearance of tissues and cellular microenvironments. Current clinical pathology relies largely
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utilizing ex vivo airway epithelial cell models, including air-liquid interface (ALI) culture systems. Experience analyzing and interpreting transcriptomic datasets (e.g., RNA-seq). Experience working with
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approach for a detailed understanding of phase separation control of gene expression; 2) molecular, cellular and biochemical characterization of defense signal flow through membrane-less condensates; 3
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. The postdoctoral researcher will take a leading role in addressing these questions using complementary molecular, cellular and structural approaches. The work will include recombinant protein production, structural
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of single-cell multi-omics data (scRNA-seq, scATAC-seq, Multiome) to reconstruct gene regulatory networks in 3D forebrain dorsal organoids to determine pathophysiological consequences of aberrant NR2F1 dosage
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. Deliver the correlation between PSC composition and antibacterial efficacy across planktonic, biofilm and clinical conditions. Assess in vitro cytocompatibility of selected PSC formulations in cell lines
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, and receptor–protein interactions within the cell membrane. These investigations aim to reveal how receptor behavior changes in chronic diseases such as heart failure and ischemic cardiomyopathy
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‑pathogen and host‑microbiome interactions in metabolic, autoimmune, and oncologic diseases using a combination of molecular biology, cell signaling, immunology, and multi‑omics approaches. Particularly
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microscopy-based imaging, flow cytometry, single-cell omics technologies, and functional immunological analyses. The research group is located in the MediCity Research Laboratory of the Faculty of Medicine