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laboratory (http://www.garglab.org ) uses approaches from genomics, molecular biology, systems biology, and data science to understand cellular heterogeneity. We want to understand how cell systems with
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samples. The lab seeks to uncover new therapeutic targets in cancer by bridging single-cell sequencing with high-throughput immune/cancer cell co-culture screens (PMID: 33483338, PMID: 40799546, PMID
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, an understanding of computational data analysis is highly encouraged and supported. Research activities may include: Culture and maintenance of mammalian cancer cell lines and our established pre-clinical platform
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calling, annotation Perform rare-variant and association analyses across patient cohorts Integrate genomic data with single-cell, spatial, and other omic datasets Develop and maintain reproducible analysis
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allograft rejection/failure is highly desirable. The approaches are founded on interpretation of large data sets from human genome level sequence data and/or mouse cell type specific transcriptome sequence
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Postdoctoral Associate | Mitochondrial Genomics | Lake Lab — Yale University, Department of Genetics
We are seeking a motivated postdoc to join our growing team in the Yale University Department of Genetics. Our lab uses experimental and computational methods to investigate cellular and health
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the following areas is highly valued: background in virology, respiratory biology, or mucosal immunology; prior wet lab experience including cell culture, immunological methods (e.g. flow cytometry), virology and
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twins of patients, modeling disease biology across scales—from genome to cell to circuit—to enable proactive, personalized intervention. By combining large-scale human data (genomes, single-cell and
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and adaptive immune signatures of vaccine responses in vulnerable populations, such as transplant recipients and individuals with sickle cell disease, using tools including multicolor flow cytometry
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, bioengineering, or a related field - Strong background in molecular biology, cell biology, immunology, animal models, neuroscience, or translational research - Demonstrated ability to conduct independent research