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therapies. In our laboratory, we have established and validated a panel of genetically heterogeneous PDAC models. These studies have shown that malignant-cell genetics shape distinct, therapeutically
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exactly the immue system detects and responds to pre-cancereous lesions. Nevertheless, it is known that the activatin (or deactivation) of anti-cancer immune cells involves many different cell-types
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their website at https://www.naritalab.com/ Our laboratory investigates the biology of preneoplastic cell states, with particular interest in how changes in cell functional identity and plasticity are controlled
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experience in cleanroom microfabrication, actuator design and characterisation, finite element modelling, rheology, ex vivo tissue methods and cell culture. You will work across engineering and life sciences
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infection. This project will ask how antibiotics reshape phage-bacteria interactions, resistance evolution, and cell-to-cell variation in bacterial responses. The student will combine experimental evolution
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with no cure, and we urgently need new ways to understand and treat it. This exciting PhD project combines cutting-edge stem cell technology, 3D bioprinting, brain cell models, and advanced genomic
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dependencies in cell and primary patient models. Jointly supervised by Dr. Tianyi Zhang and Professors Guy Pratt and Sarah Dimeloe who will provide supervision in genome biology, immunology and immunotherapy and
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across development and aging. Using cutting-edge multi-omic and single-cell datasets generated by our team and international collaborators, this bioinformatics project will investigate how the X and Y
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Transcription Factor Interfaces in Pancreatic Cancer". This project will use innovative molecular and cellular approaches to explore new ways of understanding and targeting pancreatic cancer. You will help build
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, and the sector urgently needs reliable methods to detect and understand it. At present, however, plating remains extremely difficult to measure non-destructively in industry-relevant cell formats