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, maintenance and relapse of acute myeloid leukemia (AML). We use various models to dissect critical cellular and molecular mechanisms of AML initiation and maintenance (Stavropoulou et al. Cancer Cell, 2016
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funded through the EU Research Framework Programme? Not funded by an EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Ph.D. position in immune cell
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mechanisms of AML initiation and maintenance (Stavropoulou et al. Cancer Cell, 2016; Lopez et al., Cancer Discovery, 2019, Forte et al., Cell Metabolism, 2020; Leonards et al., Nat Commun 2020, Piqué et al
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aiming at reversing this process are still lacking. By exploring the intimate mechanisms regulating CD8 T cell exhaustion, our group aims to identify innovative opportunities to reverse this process and
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represents a central limitation to current anti-cancer immunotherapies and strategies aiming at reversing this process are still lacking. By exploring the intimate mechanisms regulating CD8 T cell exhaustion
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in tissue damage and repair with a focus on mechanistic cellular and molecular studies. The successful candidate should integrate a variety of experimental approaches to gain insight
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Your position Corticosteroids regulate essential physiological processes. Substances altering their production, cell-specific metabolism or receptor-mediated signalling can aggravate various
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, CD8 T cell exhaustion represents a central limitation to current anti-cancer immunotherapies and strategies aiming at reversing this process are still lacking. By exploring the intimate mechanisms
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altering their production, cell-specific metabolism or receptor-mediated signalling can aggravate various diseases including inflammatory, cardio-metabolic as well as developmental and reproductive disorders
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this process are still lacking. By exploring the intimate mechanisms regulating CD8 T cell exhaustion, our group aims to identify innovative opportunities to reverse this process and unleash the full potential