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in the growth of melanoma cell xenografts in isogenic mice; to determine how GATA6 modulates the tumor immune microenvironment (immunohistochemical staining of tumor sections, transcriptomic analyses
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the experimental and bioinformatics analysis components—is essential. Proficiency in classical genomics techniques (RNA-seq, ChIP-seq, etc.) Proficiency in mouse ES cell culture and in vitro differentiation
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potential immunotherapeutic applications. They will subsequently characterize and evaluate their in vitro activity using isolated murine and human immune cells. Finally, they will assess the therapeutic
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, integrating statistical inference, machine learning, and population genetics. We will develop advanced computational methods to characterize the functioning of T- and B-cell repertoires. The goal is to build
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-Chem simulations for modeling aerosols and clouds in the Arctic region. - Analysis of the interactions between aerosols, clouds, and climate using data from the simulations. - Validation of the models
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analyses from various 2D/3D cell models. He/She will produce and characterise peptides derived from the extracellular matrix. He/She will analyse the results and contribute to their application. He/she will
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, biochemistry and cell biology. The agent will conduct experimental biology activities, including cell biology experiments, biochemical assays, and biochemical and molecular biology techniques. They will analyze
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numerical simulations and analytical calculations, (iii) data analysis by programming, e.g. python and matlab, (iv) help and guide of Ph.D students in the team, (v) writing research reports, publishing
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fundamental and clinical point of view. It combines diverse approaches ranging from genetics and cell biology to biophysics and from human cognition and psychoacoustics to computational neuroscience to create a
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, theoretical modelling and numerical simulations. The team focuses on model materials with controlled physical parameters, enabling quantitative comparisons between experiments, models and simulations, with