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Field
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condition, but its clinical management relies heavily on HbA1c – a biomarker affected by distinct pathways: glucose metabolism (glycaemic) and independent red blood cell biology (non-glycaemic). This means
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considered an advantage: experience in designing and conducting experiments aimed at linking the biological activity of a compound with its molecular mechanism of action; experience with eukaryotic cell
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white matter. The network aims to strengthen the full translational pathway, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and
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that can interact with human cells and tissues with high spatial and temporal resolution. You will embark on a new project focused on the development of 3D-printed hydrogel bioelectronics for neural
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cell electrochemistry and degradation mechanisms. The project will involve experimental campaigns at central facilities and close collaboration with beamline scientists and industrial partners within WMG
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at the IBDM (Institute of Developmental Biology of Marseille) within the “Physical approaches to cell dynamics and tissue morphogenesis (PoM)” team, and at IUSTI (University Institute of Industrial Thermal
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biology to better understand mechanisms of treatment resistance and identify new therapeutic targets. To achieve this, we apply state-of-the-art technologies for molecular tumor analysis using both solid
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, integrating these data to investigate disease mechanisms at unprecedented resolution. You will investigate how genetic variation, including differences in mtDNA variant levels between cells, influences cellular
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and screen genetically encoded peptide libraries in cancer cell models, with the aim of identifying molecules and mechanisms that influence cancer cell behaviour. The role offers an excellent
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applications. By tracking ^89Zr-labelled cells over extended periods of up to one month, you will investigate immune cell homing and trafficking, generating new insights into disease mechanisms and the potential