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Field
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microenvironment, and which states ultimately suppress or promote tumour development. The PhD project will investigate the molecular and epigenetic mechanisms underlying transitions between preneoplastic cell states
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unique expertise in human neuropathology. The team has extensive experience with human tissue, histology, cell culture, microscopy and advanced molecular techniques, including transcriptomic analyses
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the biological mechanisms that drive tumour initiation and subsequent growth holds significant promise for improving patient outcomes. This PhD project explores the novel concept that cell fusion between two
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development and cancer biology, the student will build tools that connect molecular mechanisms of gene regulation to cellular phenotypes in cancer cells, and use them to dissect how ecDNA is organised
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experiments using cancer and stromal cell models, including CRISPR/Cas9-based genetic approaches to investigate Cx43-dependent mechanisms. Establish and characterise tumour–stromal co-culture and 3D models
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– Friday, 8 a.m. – 5 p.m. Summary The laboratory is seeking a highly motivated and responsible Postdoctoral fellow to perform NIH-funded R01 award. The primary focus of the lab is exploring the mechanism
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characterised. Their tasks will involve investigating the molecular and cellular mechanisms involving these proteins and determining their role in the phenotype of glioblastoma cells, in particular
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This is a fully funded 3-year PhD studentship to join the group of Dr Tianyi Zhang in the Department of Cancer and Genomics Sciences to investigate molecular mechanisms of genome regulation in
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to uncover fundamental mechanisms of brain development while developing highly transferable research skills. These studentships are funded through GW4 BioMed3 MRC Doctoral Landscape Programme and consist of UK
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with no cure, and we urgently need new ways to understand and treat it. This exciting PhD project combines cutting-edge stem cell technology, 3D bioprinting, brain cell models, and advanced genomic