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Field
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leukaemia (AML) is a highly lethal disease in which the overall survival rate has not improved over the last 25 years. It is now estimated that 20-30% of patients with cancer die due to cardiovascular causes
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multimodal experimental data, physics-based modeling, and machine learning techniques to understand, explore, and predict the multiscale behavior of the human heart and cardiovascular system. More information
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an increased production of myeloid cells at the expense of the adaptive immune lymphocytes. This has been associated with an increased risk of age-related conditions including cardiovascular complications
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that do not resemble the nature of the tissue surrounding it, such as a cardiovascular stent. This PhD project will design, synthesize, and operate a new multi-responsive soft miniaturized robot/device
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techniques. In vitro research with purified recombinant proteins and cell-based assays are complemented by in vivo studies with transgenic mouse models of cardiovascular diseases, which were established by our
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Applications are invited for postgraduate research leading to a PhD degree in Biomedical Engineering within the subject area of Biomechanical Modelling. Biomechanical Modelling has shown great
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and cardiovascular physiology in the Czech Republic. Using molecular, cellular and animal models, we tackle mechanisms of serious human medical conditions including autism spectrum disorder, epilepsy
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transgenic mouse models of cardiovascular diseases, which were established by our group. The project also develops and applies biophysical methods with fluorescent protein-based sensors for structural and
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study how this contributes to local matrix deposition. This fundamental research project will involve cell culture experiments with confocal microscopy and in vivo mouse models for atherosclerosis. As a
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-threatening event for which no curative therapies exist. In this project, single-cell and/or spatial transcriptomics approaches in aortic tissue samples of transgenic TAAD mouse models will be used to further