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biology, enzymology, crystallographic fragment screening, and structure-guided drug discovery to define novel mechanisms of RT inhibition and develop new approaches for targeting protein–nucleic acid
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metabolic dependencies in cancer. We discovered a targetable metabolic vulnerability that is induced downstream of mTORC1 in cancer, and can be exploited using clinically approved therapeutics to selectively
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) the regulation and function of tumor suppressor p53 and its gain-of-function mutants in cancer; 2) the role of tumor suppressors, including p53 and its target genes, in tumor microenvironment and tumor immunology
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Associate will work on a project in a laboratory dedicated to studying the molecular pathogenesis of Parkinson’s Disease and related disorders, identifying therapeutic targets and testing new therapeutic
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updates for all assigned studies. Under the instruction of the Principal Investigator, drafts materials for IRB submissions and renewals. Under the direction of the Principal Investigator, supports targeted
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discovery, membrane-tethered cytokine technologies, tumor resistance mutations, target antigen discovery, and preclinical development of new TCR-based treatments. There will be opportunities to work in an
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to strengthen the graduate applicant pool, while respecting program-level authority over final admissions decisions. Leads enrollment planning and forecasting efforts, designing and implementing targeted
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Laboratory studies how metabolic networks are coordinated to promote cell growth, and how to leverage that understanding to exploit metabolic dependencies in cancer. We discovered a targetable metabolic
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of Parkinson’s Disease, identifying therapeutic targets and testing new therapeutic agents. Student Assistant will work in a new lab as part of a highly integrated research team utilizing a variety of laboratory
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Destruction Course Texas Engineering Extension Service (TEEX) Threat and Risk Assessment Course Department of Homeland Security (DHS) Protective measures Course Department of Homeland Security (DHS) Soft Target