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broad range of genes involved in numerous anti-cancer programs, including cell cycle arrest, DNA repair, senescence, and apoptosis. However, in most cancer types, targeted induction of p53 by small
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arrest, DNA repair, senescence, and apoptosis. However, targeted induction of p53 by small molecule inhibitors of a key upstream negative regulator MDM2 leads in most cancer types to a reversible
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in both the mitochondrial dysfunction associated with neurodegeneration and the metabolic advantage and resistance to apoptosis exhibited by cancer cells. To this end, RNA molecules encoding
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-activity in primary cells Caspases are best known for their role in apoptosis. However, although many hundreds of substrates of caspase-3 have been described, there is arguably not a single one whose
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therapies that induce apoptosis or mitotic catastrophe, for example [1,2]. In particular, these parameters have been used to show whether or not preclinical or clinical breast cancer tumors are
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and nanomedicine Employer VSB-Technical University of Ostrava Location Ostrava (CZ) Salary Will be disclosed at later stage Closing date 24 Oct 2026 Website https://mel.vsb.cz/en/ View more categories