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compounds that enhance the activity of existing antifungal agents, reverse antifungal resistance, and reduce drug-associated toxicity. These studies build on our recent publications describing pantothenate
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-based perturbations, base/prime editing, and targeted epigenetic modulation). Functional genomics in neuronal systems, including transcriptomic and epigenomic profiling. Model systems such as human iPSC
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based at Yale School of Medicine for 25 years. It is an international, collaborative network of epidemiologists, statisticians, pharmacoepidemiologists, and clinicians with an exceptional record
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, Life Sciences, or a related discipline, with demonstrated hands-on experience in LC-MS-based metabolomics. The candidate will also be encouraged to apply for external postdoctoral funding and contribute
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cellular biology approaches. The Park Lab develops human stem cell-based neural models to investigate molecular and cellular mechanisms regulating neurodevelopment and neural function, and to understand how
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medical imaging and preclinical models are also strongly encouraged to apply. Any wet lab experience for ex vivo tracer validation studies is a plus. The successful candidate will – based on their research
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of greenhouse gases (specifically methane) from vegetated wetlands, coastal systems, and inland waters, with a focus on advancing process-based science and informing strategies to reduce greenhouse gas emissions
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uncertainties in warming feedbacks on methane, provide improvements that can advance a process-based understanding of feedbacks, and make connections with existing or potential mitigation interventions to reduce
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validate exosome-based biomarkers for treatment responses in ongoing interventional studies. · Integrate exosome data with imaging and other fluid biomarkers using advanced computational tools. Required
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and cellular mechanisms underlying these disorders using cell-based assays, blood vessel organoids, and zebrafish and mouse models, working alongside neurosurgeons, computational scientists, and