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program to a driver of pathology? We investigate how senescent cells control tissue plasticity and microenvironmental dynamics during regeneration, aging, and cancer, and how these processes can be
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and analysis pipelines for real-time performance, enabling adaptive imaging and feedback control Design active-learning and retraining strategies to robustly generalize to new microbial communities
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sensitivity analysis; · Developing advanced multiphase and multi-species models and performing CFD simulations to investigate flow, mass, momentum and energy transfer within the injector
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and evaluate restoration of immunity leading to functional cures. The project will investigate virological and immunological parameters using molecular biology, conventional and spectral flow
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cells, immune cells and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy and unbiased approaches such as single
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by spectral flow cytometry and scRNAseq, while CD4+ T cell / B cell interactions will be probed by confocal microscopy. The project will then aim at devising a new generation LO chip model that better
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,J Spielbauer, M Berard, M Lecuit, IG Boneca. 2022. Microbiota-induced active translocation of peptidoglycan across the intestinal barrier dictates its within-host dissemination. Proc Natl Acad Sci U S
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. Solid foundational knowledge of tumor immunology and cancer biology Knowledge of cell biology techniques, such as microscopy and flow cytometry Practical experience with cell culture and tumor cell
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motor control, behavioral readouts across species offer the potential to overcome one grand challenge in neuroscience: bridging the gap between molecular, cellular, and systems levels. Importantly, the
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focuses on experimentally demonstrating coherent spin shuttling, shuttling-compatible high-fidelity qubit control and further ingredients for a shuttling-based architecture, using devices from