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specializes in precision cardiovascular medicine, leveraging cutting-edge approaches such as human iPSC-derived 2D cardiovascular cells, 3D vascularized cardioids, CRISPR gene editing, high-throughput CRISPRko
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within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and
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cancers. The objectives of the project involve elucidating the 3D-structures and biomolecular function using cryo-EM and cryo-ET and rational vaccine design. The employer retains the right to change
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and eosin staining, novel antibody staining/quality control testing, antigen retrieval processes, in situ hybridization, RNAScope, 3D spatial techniques such as 10XVisium and other emerging imaging
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, University of Glasgow. https://theses.gla.ac.uk/41141/ B. Cortese, G. Gigli, M. Riehle, Mechanical Gradient Cues for Guided Cell Motility and Control of Cell Behavior on Uniform Substrates. Adv. Funct. Mater
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within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and
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. Preferential Requirements Additional professional experience in laboratory management, as indicated in the CV and/or motivation letter; Knowledge in 3D cell models, including spheroids, cloning and CRISPR/Cas9
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biological and microbiological characterization of polymer biomaterials, (nano)composites, and nanoparticles, as well as practical knowledge of advanced fabrication methods (including electrospinning and 3D
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procedures. Experience with cell culture and basic in vitro biological assays. Familiarity with good laboratory practices, risk assessment, chemical safety, and laboratory-quality documentation. Experience
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dimensionality (e.g., inside carbon nanotubes, 3D porous carbons), (2) behaviour under applied bias in confinement. Spatially resolved data from STEM and EELS will be correlated with volumetric measurements from