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. Transgenerational epigenetic inheritance is increasingly recognised as a way in which changes in gene expression can be passed across multiple generations without changes in underlying DNA sequence. Mechanistic
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well as evaluating the effects of epigenetic inhibitors on CCA growth in vitro and in vivo. The post-holder must hold a Ph.D. degree in cancer biology and immunology. You will report to Dr. Shijie Cai and work with
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, enabling us to study these diseases directly from patient samples, which are complemented by a wealth of clinical data. Our in-house capabilities include the generation of single cell epigenetic and
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subject area and have prior experience of working in a molecular biology laboratory. You will have a keen interest in X chromosome inactivation/epigenetics research fields and have experience with
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technology, the Song research group have developed cutting-edge technologies in epigenetics and epitranscriptomics to elucidate biological functions and develop clinical applications. In this role, will
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at the intersection between chromosome biology, flow cytometry, microfluidics and molecular/epigenetic analysis. The group’s current work focuses on determining the repertoire and role of proteins that remain bound
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of chromatin replication using single-molecule imaging, biochemical and biophysical approaches. The project aims to uncover how specific epigenetic marks and histone variants affect nucleosome dynamics during
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mechanisms of chromatin replication using single-molecule imaging, biochemical and biophysical approaches. The project aims to uncover how specific epigenetic marks and histone variants affect nucleosome