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iPSC/organoid models equipped with genomic, computational, 3D imaging, behavior, stem cell, biomaterial, as well as molecular, cellular, and circuit approaches (Cell Stem Cell., 2023, PMID: 37863055; Sci
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individuals at high risk of developing Alzheimer’s disease, as well as to test the efficacy of a newly developed small-molecule therapeutic in vitro and in vivo using our unique transgenic rat models
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mouse genetics, multicolor ‘Rainbow’ and Tetrachimera mouse models, surgery models in rodents, flow cytometry, single cell omics, cell & molecular biology approaches to pursue diverse questions on how
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of this project is to map the molecular networks controlling the fate of microglia towards these antagonistic activities using a mouse model of multiple sclerosis, and to functionally validate the core genes
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characterized by a strong Th17 cell response and enhanced colonization resistance to pathogens. Our work uses a combination of wild-type and knock-out gnotobiotic mouse models, in vitro hypoxic growth conditions
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of autoantigen-specific Tregs and Teffs in humans, the selection of optimal TCR to produce protective Tregs, innovative humanized T1D pre-clinical models to test their efficacy and safety, the development
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The Münch lab and Institute of Molecular Systems Medicine at the Goethe University Frankfurt (https://molsysmed.de/ ) invites applications for 2 Postdoctoral positions(f/m/d, E 13, TV-G-U) to study
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(Level B) $107,276 to $126,894 per annum plus an employer contribution of 17% superannuation applies. Fixed term, full time position available for 24 months. Develop AI-driven digital tissue models
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Postdoctoral position is sought for a postdoc with demonstrated experience in mouse models of disease, molecular biology, and electrophysiology. The candidate is expected to continue our work
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Postdoctoral Position in Molecular Mechanisms Regulating Placenta Development NIH-funded postdoctoral position is available to investigate molecular mechanisms controlling hemochorial placentation