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of the doctoral student This project aims to uncover the principles of protein inheritance and its impact on aging and rejuvenation. We will utilize budding yeast as a model organism to investigate how cells
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network analysis to develop methods that transition analysis from cohort-level to patient-specific protein-protein interaction networks, using in-house generated and publicly available data. Specifically
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documented experience with standard cellular techniques, cellular viability/survival, clonogenic assays and molecular biology techniques, eg qPCR, cloning, confocal imaging, protein purification and virus
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, restriction digestion), gel electrophoretic techniques in addition to techniques in molecular cloning and transgenic protein production workflow. The ability to conduct lab work and document results in a
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for a student with a background in molecular biology who is passionate about pursuing translational research. A strong interest and experience in immunology, autoimmunity and protein analysis is
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. The project will characterize, and functionally test, how the early embryo is regulated with studies at genetic, epigenetic and protein levels. What do we offer? A creative and inspiring environment full
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from different proteomic platforms within the TwinGene cohort. These clocks will be explored using protein quantitative trait loci (pQTL), with the ultimate goal of identifying new genetic loci related
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exploring how deep learning models can aid the deciphering of RNA-binding protein codes that control cell-type specific splicing. What do we offer? A creative and inspiring environment full of expertise and