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research on appropriate statistical and machine-learning methodology in the areas of large scale omics data such as genomics, transcriptomics, proteomics/metabolomics and the integration of these, as
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, apoptosis requires mitochondria to activate proteases call caspases. Apoptosis is a silent form of cell death that fails to evoke an immune response. We have found that killing cells under caspase inhibition
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mouse, labs around the world have found that many human diseases can be modelled cheaply, quickly and ethically in the simple genetic model fly, Drosophila melanogaster. This can provide huge advantages
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Yin), to applied models (Prof A Hart). The implications of the different repair strategies on the cells genomic and proteomic response is being investigated in collaboration with the Glasgow Polyomics
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with vascular physiology and molecular approaches, including transcriptomics and/or proteomics, to identify novel mechanisms. Importantly, you will validate these mechanisms in patients. This project can
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Our Plant Science research covers topics such as plant-environment interactions, cell signalling, cell and membrane biology, protein structure and function, gene regulation, synthetic biology
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interrogate immune – microbiome interactions within adenoma and surrounding colonic biopsy tissue using techniques including immunohistochemistry, RNAseq, RNAscope, and state of the art spatial proteomic
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Research projects Research projects Biomedical Engineering PhD opportunities Doctoral Training Centre in Cell & Proteomic Technologies: research themes Biomedical diagnostics Biomolecular mass spectrometry
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wastewater treatment plants therefore contains a chemical load that reflects the normal human exposome. Biosolids are routinely used as an agricultural fertilizer and when animals are grazed on biosolids
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focus. Due to evolutionary principles being fundamental to all aspects of biology, our research activities are naturally linked with those of other research themes within the institute and throughout