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Cancer Metabolism, Dr. Shuck’s lab is focused on elucidating the mechanisms linking diabetes and cancer. Her lab utilizes a multi-prong approach using human, mouse, and cell models to determine the role of
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homeostasis, and healthspan/lifespan. The lab specializes in detailed studies of signaling/trafficking/exocytosis, using primary human and rodent islet cells, skeletal muscle cells and adipocytes. The position
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candidate, you will: Develop and modify laboratory protocols for brain tumor research. Conduct tissue culture, including the characterization and development of murine and human cell lines. Perform in vivo
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data analysis is highly preferred. · Multiple First author publication in high-impact journals · Previous experience in working with animal models of human cancers · Literature
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in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes. The major ongoing projects are investigating miRNA biomarkers
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, including first-in-human studies with genetically engineered hematopoietic stem and progenitor cells (HSPC) and T cells. As a successful candidate, you will: · Conduct research on next-generation
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using transgenic and transplantation mouse models of lymphoproliferative diseases, primary cells from patients, humanized mice, gene editing, classical molecular, cell biology, and biochemistry, and
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, experience in sequencing or protein structural data analysis is highly preferred. · Previous experience in working with animal models of human cancers · Literature knowledge of one of the three
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, or immunotherapy. Previous experience in working with human specimens and development of novel, innovative cancer biomarkers. Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed
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intrafemoral transplantation assays, subcutaneous pump implantation for delivery of candidate therapies, utilizing humanized mouse models, conducting pre-clinical testing of immunotherapies in