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cure several cancer types originating from blood cells. However, the success of gene therapy has not yet been extended to other cancer types, where two major challenges are i) difficulties in identifying
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variety of therapeutic targets. Specifically, the project will aim to develop innovative genome-editing solutions for gene therapy on autologous hematopoietic stem cells Gene therapy using autologous
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, stem cells, human pluripotent cells, and several molecular tools to investigate fundamental mechanisms of cancer, COVID-19, AIDS, brain, and immune disorders. Under supervision, the Research Associate
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(>50% at 5 years in severe cirrhosis). The risk of acute hepatocellular failure makes 1 in 5 liver tumour patients ineligible for potentially curative surgical removal. Question: Can gene therapy improve
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University Health Board and Velindre University NHS Trust. The CCRH will drive the immuno-oncology, cell therapy and Advanced Therapy Medicinal Products (ATMP) research portfolio in Cardiff in both haemato
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private partners, who want to participate in the gene therapy space. Currently we are positioned to lead another round of vector innovation and establish preclinical and clinical proof-of-concept in
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the UK biomedical community and focuses on preclinical research using mouse models, which supports clinical research and therapy discovery. The MRC is an excellent place to develop yourself further and a
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Stem Cell Institute includes six (6) stem cell Centers led by Center Directors and Co-Directors. One of these centers, the Sanford Advanced Therapy Center (ATC), provides fundamental tools and services
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-modifying/curative therapy/therapies for Alzheimer´s disease (AD) mainly using growth factors, with focus on encapsulated cell (EC Biodelivery) implants releasing nerve growth factor (NGF) and brain derived
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), an Institute for Technological Research (IRT Jules Verne), the National Institute of Health and Medical Research (Inserm) and several grandes écoles (Centrale Nantes, École des Beaux-Arts Nantes Saint-Nazaire