Research Associate (two posts) (ref. 17396)
School of Clinical Sciences
- Fixed Term Contract (three years)
- Level b in Pathway 2
- Closing date for applications:
- 9:00am 31 Aug 2012
We currently have two vacancies for Research Associates jointly co-supervised by the School of Clinical Sciences and the Department of Engineering Mathematics. One post has a biological emphasis and the other a mathematical emphasis.
The purpose of the work is to undertake research into mechanisms of hormone signalling action. The project is funded by the BBSRC and is led by Professor Craig A McArdle (School of Clinical Sciences) and by Dr Krasimira Tsaneva-Atanasova (Department of Engineering Mathematics). It focuses on understanding signalling of the neuropeptide gonadotrophin-releasing hormone (GnRH), in biochemical, molecular and mathematical terms.
Post 1 will involve a number of standard molecular and cellular biological techniques (cell culture, transfection, transduction, preparation of plasmid and viral vectors, western blotting, transcriptional reporters, and fluorescence microscopy) as well as automated fluorescence microscopy. GnRH is secreted in brief pulses and its effects are dependent on pulse frequency and this project will focus on cellular frequency decoding mechanisms. The importance of the work lies in the fact that GnRHR are major therapeutic targets for treatment of infertility and hormone-dependent cancers.
Post 2 will involve development and analysis of computational models of both the physiology and phenomenology of GnRH signalling. These models will be used to probe for mechanisms that govern GnRH frequency decoding. GnRH is secreted in brief pulses and its effects are dependent on pulse frequency and this project will focus on cellular frequency decoding mechanisms. The importance of the work lies in the fact that GnRHR are major therapeutic targets for treatment of infertility and hormone-dependent cancers, and in the utility of this system for understanding the mechanisms of frequency decoding in biological systems.
Please state in your application which post(s) you wish to apply for.
If successful, you may be appointedeither on a fixed-term or an open-ended contract depending on the extent of your previous relevant research experience. Three years’ appropriate and relevant experience at another higher education institution would normally lead to an appointment on an open-ended contract. Further information can be found at www.bristol.ac.uk/hr/ftc/
Download full details:
- 17396 post 1.doc
- 17396 post 2.doc
If you do not have Microsoft Word you may require a Word document reader to open this file: Open Office - download, or Word viewer are available.
- Contact for informal enquiries:
- Professor C McArdle (Craig.Mcardle@bristol.ac.uk | 0117 331 3077)
- Dr K Tsaneva-Atanasova (K.Tsaneva-Atanasova | 0117 331 5603)
Research Fellow In Health Economics, University of Bristol, Bristol, United Kingdom, 6 months ago
Research Fellow in Health Economics Vacancy number: ACAD101072 School of Social and Community Medicine £40,847 - £45,954 Applications are invited for an experienced health economist to join the NI...
Research Fellow In Verifiable Autonomy, Ref:1440517, University of the West of England, United Kingdom, 6 months ago
Department Engineering Design & Mathematics Campus/location Frenchay campus Duration of post Fixed term Fixed term period (yrs/mths) Until 31 December 2017. Post is open to: External and internal ...
Postdoctoral Research Fellow In Computer Graphics And Visualisation, Bournemouth University, Bournemouth, United Kingdom, 9 months ago
Postdoctoral Research Fellow in Computer Graphics and Visualisation (Fixed-term) Ref: MED494 Starting salary from £27,318 to £31,644 per annum with further progression opportunities to £34,565 The...
Chair Of The Heilbronn Institute For Mathematical Research, University of Bristol, Bristol, United Kingdom, about 2 months ago
Chair of the Heilbronn Institute for Mathematical Research School of Mathematics Vacancy Number: ACAD101248 The Heilbronn Institute for Mathematical Research (HIMR) is seeking to appoint an outsta...
The Leverhulme Trust Research Fellow In Bio Inspired Engineering , Ref:1423151, University of the West of England, United Kingdom, 7 months ago
Department Computer Science & Creative Technologies Campus/location Frenchay campus Duration of post Fixed term Fixed Term end date 30 Nov 2017 Post is open to: External and internal candidates Cl...
Vice Chancellor's Postdoctoral Fellowships, RMIT University, Australia, United Kingdom, 3 months ago
RMIT Research & Research Training is global, partnered and making an impact RMIT University is a global university of technology and design. RMIT University has an international reputation for exc...