MRC CASE award: Structural characterisation of CD81 / Claudin-1 receptor complexes as host targets for Hepatitis C anti-viral drug discovery

about 2 years ago



MRC CASE award: Structural characterisation of CD81 / Claudin-1 receptor complexes as host targets for Hepatitis C anti-viral drug discovery
Marie Curie Actions Co-fund. More
Marie Curie Actions. More
European Research Council. More
'HR Excellence in Research' logo awarded to institutions actively implementing the European Charter and Code for Researchers. More
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1st Supervisor: Professor Jane McKeating, University of Birmingham
2nd Supervisor: Susanne Bethell, Astex Therapeutics Ltd
Hepatitis C Virus (HCV) poses a global health problem, with over 170 million chronically infected individuals worldwide. HCV entry into cells is dependent on tetraspanin CD81 and tight junction proteins Claudin-1 and Occludin1. Fluorescence resonance energy transfer occurs between fluorescent tagged receptors expressed in hepatoma cell lines and protein stoichiometry at ...


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Research Fields

Medical sciences

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Programme Description
Eligible destination country/ies for fellowsUnited Kingdom
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehttp://www.nature.com/naturejobs/science/jobs/275236-MRC-CASE-award-Structural-characterisation-of-CD81-Claudin-1-receptor-complexes-as-host-targets-for-Hepatitis-C-anti-viral-drug-discovery
Fellowship's Details
Career StageExperienced researcher or 4-10 yrs (Post-Doc)
Research ProfileNot defined


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