MRC CASE award: Structural characterisation of CD81 / Claudin-1 receptor complexes as host targets for Hepatitis C anti-viral drug discovery
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1st Supervisor: Professor Jane McKeating, University of Birmingham
2nd Supervisor: Susanne Bethell, Astex Therapeutics Ltd
Hepatitis C Virus (HCV) poses a global health problem, with over 170 million chronically infected individuals worldwide. HCV entry into cells is dependent on tetraspanin CD81 and tight junction proteins Claudin-1 and Occludin1. Fluorescence resonance energy transfer occurs between fluorescent tagged receptors expressed in hepatoma cell lines and protein stoichiometry at ...
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|Eligible destination country/ies for fellows||United Kingdom|
|Eligibility of fellows: country/ies of residence||All|
|Eligibility of fellows: nationality/ies||All|
|Website of Fellowship Programme||http://www.nature.com/naturejobs/science/jobs/275236-MRC-CASE-award-Structural-characterisation-of-CD81-Claudin-1-receptor-complexes-as-host-targets-for-Hepatitis-C-anti-viral-drug-discovery|
|Career Stage||Experienced researcher or 4-10 yrs (Post-Doc)|
|Research Profile||Not defined|
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