PhD position in Medical Science with orientation towards Molecular Biology

Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.

The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.

We are looking for a PhD student in Medical Science with an orientation towards Molecular Biology and a special interest in microbial host pathogenesis. The position at the Department of Molecular Biology at Umeå University is temporary for four years to start 1 May 2024 or as agreed. The PhD student will participate in activities provided by the Department of Molecular Biology, the Laboratory for Molecular Infection Medicine Sweden (MIMS), and the Umeå Centrum for Microbial Research (UCMR), thus providing interaction with researchers from different research fields and access to various scientific and technical expertise. 

https://www.aurora.umu.se/en/organisation-and-management/organisation/faculties/faculty-of-medicine/doctoral-studies/

The project investigates the role of bacterial secreted effector molecules in host pathogenesis and their potential use as cancer therapeutics. It involves work with mammalian cell cultures, human intestinal organoids, and Acanthamoeba castellanii as a model organism. We will use bacterial genetics, high-throughput image screening, biophysical/biochemical methods, and advanced microscopy techniques. A person who is employed as a PhD student shall primarily devote his-/or herself to his/her own education. The project and research environment will give the dedicated student the opportunity to train as a first-class researcher.

Applicants must hold a University degree equivalent to a European University Master degree or completed course requirements of at least 240 credit points, of which at least 60 credit points should be at second-cycle level. Required is a minimum of 30 credits in the main field of chemistry, including at least 7.5 credits biochemistry; 45 credits in the major areas of biology or molecular biology with at least 7.5 credits in genetics and 22,5 credits in the fields of microbiology, physiology and cell-and molecular biology. Additionally, at least 45 credits from second cycle studies in cell- and molecular biology including an independent work of at least 15 credits is required. You must be proficient in both oral and written communication in English.

The candidate should have prior experience with laboratory techniques, including bacterial and mammalian cell culture handling, immunoblotting, and cell toxicity assays. Experience with Acanthamoeba castellanii as a model system for studying bacterial interactions would be considered advantageous. Additional merits include knowledge or basic skills in high throughput image screening, and data analysis. You should be highly motivated and able to work productively in a team as well as independently. Excellent communication skills for interacting effectively with senior colleagues and peers are required. Great emphasis will be placed on personal suitability.

The evaluation of the ability and potential to perform well is based primarily on:

Good collaborative skills, drive and independent work ability are considered as positive merits.

A selection will be made among qualified applicants on the basis of their qualifications and their ability to benefit from studies at the doctoral level. After the selection of the suitable candidate, the process for the admission to doctoral studies will commence. An admission decision will be taken by the faculty’s director of studies.

The position is intendent to result in a doctoral degree and is limited to four years full time. If part-time teaching (max. 20%) can be offered, the employment period can be extended.

Start date 1 May 2024 or as agreed.

Wage placement takes place according to the established salary ladder for doctoral student employment.

According to the Higher Education Ordinance (Chapter 12, Section 2), the decision on employment cannot be appealed.

You apply through our recruitment system at the latest 27 February 2024. Your application must contain the following documents written in English or Swedish:

• A CV with information on education, a list of previous and current employments, and a list of publications.
• Copies of relevant degrees
• A cover letter describing research experience and interests, motivation for applying for the position
• Contact details of two to three references.

For questions regarding the position contact [email protected]

More about us

You can find more information at www.umu.se/molbiol and UCMR - Umeå Centre for Microbial Research (umu.se)