a postdoc to study the mechanism of calcium perturbation in PINK1 mutant of zebrafish, a model of Parkinson’s disease ., International Institute of Molecular and Cell Biology

Job posted by International Institute of Molecular and Cell Biology (25/07/2012 10.37)
a postdoc to study the mechanism of calcium perturbation in PINK1 mutant of zebrafish, a model of Parkinson’s disease .
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The prospective candidates should hold a PhD degree by the start of employment; have experience in molecular, cell or developmental biology; be motivated and interested in basic research and have good command of English (both written and oral). Experience in zebrafish biology will be an advantage.
Please submit your motivation letter and a CV with the contact details of two referees. Applications should be sent to: neuro-recruitment@iimcb.gov.pl
All applications must contain the following statement to allow us process your data:
"I hereby give consent for my personal data included in the job offer to be processed for the purposed of recruitment under the Data Protection Act 1997 (Dz. U. 2002 no. 101, item 926 with subs. changes)." / "Wyrażam zgodę na przetwarzanie danych osobowych w celach rekrutacji zgodnie z ustawą z dnia 29 sierpnia 1997 r. o ochronie danych osobowych (tekst jedn.: Dz U. z 2002 r. Nr 101, poz 926 z późn. zm.)."

Description

The post-doc will be working in the Laboratory of Neurodegeneration headed by Prof. Jacek Kuznicki at the IIMCB in Warsaw. IIMCB is a modern and well-equipped institute, ranked first among the biology research institutions in Poland, with a newly established zebrafish facility. The group of Prof. Kuznicki investigates the molecular mechanisms involved in neurodegeneration and memory formation, with a special emphasis on the role of calcium homeostasis and signaling at the genomic, proteomic, and cellular levels. The successful applicant will study the proteins involved in calcium homeostasis with respect to their function in zebrafish physiology. In particular basic characterization of the PINK1 mutant/transgenic line will be performed, Ca2+ homeostasis analyzed in neurons and behavioral experiments using a double transgenic zebrafish line. The position will be funded by the EU 7FP project "Fishing for Medicines and their targets using Zebrafish models of human diseases" which includes collaboration with and research visits to the leading zebrafish group in Sheffield, UK headed by Prof. Oliver Bandmann..

Nr of positions available : 1

Research Fields

Biological sciences - Biology

Career Stage

Experienced researcher or 4-10 yrs (Post-Doc)

Research Profile

Recognised Researcher (R2)

Benefits

All persons employed in the IIMCB will profit from additional insurance, health care and other benefits.

Comment/web site for additional job details

Additional job details can be found on the website of IIMCB:http://www.iimcb.gov.pl/jobs.html

Requirements
Required Education Level

Degree	PhD or equivalent
Degree Field	Biological sciences

Required Languages

Language	ENGLISH
Language Level	Excellent