a PhD Candidate/Fellow in the Laboratory of Immunology

19 Jan 2024
Job Information

Organisation/Company

Mossakowski Medical Research Institute Polish Academy of Sciences

Research Field

Medical sciences » Other

Researcher Profile

First Stage Researcher (R1)

Country

Poland

Application Deadline

15 Feb 2024 - 20:17 (Europe/Brussels)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

40

Offer Starting Date

21 Feb 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Reference Number

PI.110.1.2024

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

We are recruiting to the OPUS project No. 2023/49/B/NZ7/03915 entitled "Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficacy" funded by the National Science Centre and carried out at the Laboratory of Immunology at the Mossakowski Medical Research Institute Polish Academy of Sciences (MMRI PAS). The project is led by Dr. Małgorzata Firczuk. The Laboratory of Immunology is a new, rapidly developing scientific unit at MMRI PAS, bringing together young scientists and collaborating with numerous clinical and research teams in Poland and abroad. Currently, the Laboratory is implementing twelve projects funded by external agencies. We are looking for a candidate with a genuine passion for research, enthusiasm for discoveries, and a commitment to advancing scientific knowledge.

Information about the research project in which the candidate would participate:

Cell therapy using T cells modified with chimeric antigen receptors (CAR-T) is a novel and groundbreaking method for treating the most challenging cases of hematologic cancers, already applied in clinics, also in Poland. The project's goal is to identify new biomarkers for monitoring the effectiveness of CAR-T cell therapy. In particular, we will investigate proteases activated in CAR-T cells after their contact with tumor cells. In collaboration with the team led by Dr. Marcin Poręba from Wrocław University of Science and Technology, a partner in the project, we plan to develop probes enabling a precise assessment of protease activity using flow cytometry and mass cytometry. It is worth emphasizing that, while the project focuses on basic research to enhance our understanding of the mechanisms of CAR-T cell activation, the results obtained also carry translational and commercialization potential.

 

Requirements

Research Field

Medical sciences » Other

Education Level

Master Degree or equivalent

Skills/Qualifications

• planning and conducting experiments
• creative work involving the analysis of current literature and initiating changes during project implementation
• analysis and interpretation of acquired data
• maintaining documentation of research results following FAIR principles
• presenting results at seminars within the Laboratory and the Institute, as well as at broader scientific forums, including national and international scientific conferences
• writing scientific publications

Specific Requirements

• status of a student/PhD student
• experience with laboratory work in the areas of biochemistry, molecular biology, experimental oncology, or immunology
• proficiency in spoken and written English
• excellent organizational skills and attention to detail
• ability to work independently and as a part of a team, strong communication skills

Additional assets:

• scientific achievements documented by international publications in journals indexed in the JCR list
• documented active participation in national and international conferences and symposiums

Languages

ENGLISH

Level

Good

Research Field

Medical sciences » Other

Internal Application form(s) needed
2024 How to apply.pdf
English
(132.2 KB - PDF)
Download
Additional Information
Benefits

• scholarship of approximately 5000 PLN gross per month for a period of up to 4 years
• innovative research challenges and unique opportunities for developing research skills
• freedom and independence in carrying out assigned tasks
• mentoring and support in professional career development
• friendly, inspiring, and supportive work environment within the large team of the Laboratory of Immunology
• opportunity to present research results at scientific conferences
• support in publishing and promoting research findings
• benefits package, including a Multisport Plus card and the option to participate in group insurance on preferential terms

Website for additional job details

https://www.imdik.pan.pl/pl/

Work Location(s)

Number of offers available

1

Company/Institute

Mossakowski Medical Research Institute Polish Academy of Sciences

Country

Poland

City

Warsaw

Postal Code

02-106

Street

Pawińskiego 5

Geofield

Where to apply

E-mail

[email protected]

Contact

State/Province

Ochota

City

Warsaw

Website

http://imdik.pan.pl

Street

5 Pawinskiego Street

Postal Code

02-106

E-Mail

[email protected]

STATUS: EXPIRED