PhD position AD-RIDDLE

28 Mar 2024
Job Information

Organisation/Company

Amsterdam UMC

Research Field

Medical sciences

Researcher Profile

First Stage Researcher (R1)

Country

Netherlands

Application Deadline

11 Apr 2024 - 21:59 (UTC)

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

36.0

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The new European AD–RIDDLE project aims to develop, test, and deploy a modular toolbox platform that can reduce existing barriers to the timely detection, and therapeutic approaches in Alzheimer’s disease (AD), thus accelerating AD innovation. By focusing on health system and health worker practices, AD-RIDDLE seeks to improve and smooth AD management at and between each key step of the clinical pathway and across the disease continuum, from at-risk asymptomatic stages to early symptomatic ones.

This project, supported by the EU Innovative Health Initiative (IHI) public private partnership, forms an interdisciplinary consortium with 24 partners. One of the aims of the project is to develop and test the AD-RIDDLE toolbox platform and its components individually and in combination in six European countries. Expected results from this cross-sectoral research collaboration include tools for earlier detection and accurate diagnosis; validated, novel digital cognitive and blood-based biomarkers; and improved access to individualized preventative interventions (including multimodal interventions and symptomatic/disease-modifying therapies) across diverse populations, within the framework of precision medicine.

Alzheimer’s Disease requires innovative approaches for early detection and prevention. Compared with standard paper-and-pencil testing, digital tools have great potential due to their higher sensitivity to early disease and better ecological validity. Moreover, by removing the need for individuals to travel for their assessment(s), sensitive, specific, and valuable cognitive measures could be captured on a large scale with ease, while offering greater cost-efficiencies, accessibility, and data aggregation.

As part of AD-RIDDLE project, we will focus in Amsterdam on the following 4 tasks:
I) Preparing a choice-menu of digital cognitive biomarkers, taking the different aspects of digital cognitive biomarkers (smartphone, tablet, computer, active vs passive monitoring) into account;
II) Perform pilot studies in different participating centers to ensure reliable remote assessment;
III) Perform a large-scale study testing digital cognitive biomarkers in real-world settings across 6 European countries (Sweden, Finland, Netherlands, Spain, Italy, UK), with repeated assessments, and including implementation measures (such as motivations and diagnostic confidence);
IV) Integrative analyses including high-dimensional data and qualitative data, using a broad mixed-methods approach, ultimately leading into guideline for optimal implementation of digital cognitive assessments.

As a PhD-student, your most important tasks and responsibilities include:

• (International) collaboration and communication with different stakeholders;
• Providing an overview of (psychometric) quality of digital cognitive assessments;
• Coordination of international data-collection and analyzing and presenting quantitative and qualitative data;
• Writing scientific papers on the above-mentioned topics, leading to a PhD-thesis;
• Active participation in Academic on-site meetings.

Requirements
Specific Requirements

• Affinity and experience with scientific research;
• Affinity with novel digital neuropsychological assessments;
• Experience with data handling, statistics and epidemiology is considered a pro;
• Good communicative skills;
• Clinical experience is considered a pro.

Additional Information
Benefits

• A flying start to your career in scientific research.
• Plenty of room for personal development with a wide range of training & development of academic skills
• Working on large-scale and own research, with motivated colleagues
• A pleasant, informal atmosphere with plenty of room for humour, music and table football!
• A contract for 12 months with the prospect of extension for the duration of the PhD program.
• Salary scale: OIO € 2.901 - € 3.677 (based on a 36 hour week), depending on qualifications and experience.
• Additional benefits including an 8.3% end-of-year bonus and 8% holiday pay. Calculate your net salary here .
• Your pension is accrued at The Dutch Pension Fund for government and education employees (ABP). Amsterdam UMC contributes 70% of this scheme
• We reimburse 75% of your OV travel costs (commuting costs).

For more information about our employment conditions, please visit our website .

Additional comments

If you have any questions about this position, please feel free to contact Sietske Sikkes, via [email protected] .

For more information about the application procedure, please contact Chey Edwards, Recruitment Advisor, via [email protected] or via 06-21487245.

A reference check, screening and hiring test may be part of the procedure. Read here whether that applies to you. If you join us, we ask you for a VOG (Certificate of Good Conduct).

Internal candidates will be given priority over external candidates in case of equal suitability.

Acquisition in response to this vacancy is not appreciated.

Website for additional job details

https://www.academictransfer.com/339603/

Work Location(s)

Number of offers available

1

Company/Institute

Amsterdam UMC

Country

Netherlands

City

Amsterdam

Postal Code

1081HV

Street

De Boelelaan 1117

Geofield

Where to apply

Website

https://www.academictransfer.com/en/339603/phd-position-ad-riddle/apply/#apply

Contact

City

Amsterdam Zuidoost

Website

https://www.amsterdamumc.org/

Street

Meibergdreef 9

Postal Code

1105 AZ

STATUS: EXPIRED