PhD Student - Cardiology (m/w/d)

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21270
PhD Student - Cardiology (m/w/d)
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from April 15th wanted at the clinic for cardiology, angiology and pulmonology.

A new opportunity for talented and motivated researcher to work as a PhD student in the research group of Dr. Manju Kumari from Department of Cardiology on DFG funded project entitled ‘Transcriptional control of cardiac function and bioenergetics regulatory circuits by type I interferon signaling’. Despite a well-known role for interferon signaling in controlling immune-metabolism in the state of obesity in mice and humans, little is known about its role in heart failure. This project aims to unravel its role in cardiomyopathy progression. Utilizing excellent transgenic mouse models, primary cell-cultute models and the most recent research technologies for big data analysis we will decipher the immune and metabolic network altered in cardiac disorders. The candidate will have the opportunity to apply for grants supporting their further research work to enhance career prospects. Our research group is a diverse interdisciplinary team and the candidate should be able to work independently, having troubleshooting and multitasking skills and capable of intellectual input for project development. Application must include a motivation letter, CV, publication list and atleast two reference letters or contact details of the referees.                                                                                                                   

• Job-ID: V000012376
• Field of application: Klinik für Kardiologie, Angiologie und Pneumologie
• Location: Heidelberg
• Start date: 15.04.2024
• Job Category: Science and teaching
• Working hours: full-/ part-time (65 %)
• Published: 06.02.2024
• Limitation:Temporary (30 months, / extension is sought)
• Contract:TV-L

Your Tasks

• To identify the transcriptome and epigenome modulated by altered interferon signaling
• To study cell-type specific gain- and loss-of-function to determine cellular and metabolic effects of factors idenfied above using transgeninc mouse models
• To identify factors regulating immuno-metabolic signaling pathways under pathophysiological conditions in mice and human models
• To learn big data analysis
• To coordinate research projects with other members in the group as and when required

Your Profile

• Master degree in Molecular Biology/ Biochemistry/Cell Biology/ Life Sciences/ related subjects
• Candidate must have experience in molecular cell biology techniques (cloning, transfection, qPCR, IHC, IP, etc.)
• Candidate must be willing to working with mouse models and gaining experience on experimental rodent models of heart failure, inflammation and obesity is expected
• Experience in cell culture- immortalized or primary is essential
• Excellent communication and organizational skills with excellent knowledge of written and spoken English

We offer

• Collectively agreed remuneration, attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers
• Goal-oriented, individual training and development opportunities (e.g. Learn and perform sequencing data analysis)
• Working with the latest techniques / technical equipment Microscopy and Flow cytometry, in vitro mutagenesis
• Possibility of doctorate
• Possibility to publish scientifically is offered and supported
• Regular team meetings
• Interdisciplinary cooperation with DKFZ for Metabolomics studies

Contact & Application

For further information please contact Manju Kumari via e-mail or phone.

Interested?

we are looking forward to your application via e-mail.

Klinik für Kardiologie, Angiologie und Pneumologie
Manju Kumari, Junior Group Leader
Im Neuenheimer Feld 350
69120 Heidelberg
Tel.: 06221 56 310561
[email protected]

Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.

The UKHD embraces diversity and values diversity.

Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21270