ERC Funded PhD and PostDoc Positions in Chemical Biology (f/m/d)

18 Jan 2024
Job Information

Organisation/Company

Heidelberg University

Department

Institute of Pharmacy and Molecular Biotechnology

Research Field

Chemistry » Biochemistry
Biological sciences » Biological engineering
Technology » Biotechnology
Chemistry » Organic chemistry
Biological sciences » Biology

Researcher Profile

First Stage Researcher (R1)

Country

Germany

Application Deadline

16 Feb 2024 - 00:00 (Europe/Berlin)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

HE / ERC

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Sunbul research group at the Institute of Pharmacy and Molecular Biology (IPMB), Heidelberg University (Germany) invites applications for PhD and PostDoc positions, funded by ERC, in the field of Chemical Biology. The project will primarily focus on the discovery and imaging of disease-related RNA interactomes. 

RNAs play a myriad of roles in cellular processes and biotechnology. Their functions are precisely mediated by interactions with other biomolecules (e.g. proteins and other RNAs). Any perturbation of these interactions can lead to serious diseases. During the past decade, we made a significant contribution to the RNA imaging toolbox by generating novel genetically-encoded fluorescence light-up aptamers (e.g. Englert et al. Nature Commun 2023; Bühler et al. Nature Chem Biol 2023; Sunbul et al. Nature Biotechnol 2021; Zhang et al. Angew. Chemie 2021; Wirth et al. JACS 2019). Using this toolbox and harnessing synthetic chemistry, biophysics, and molecular biology, we now aim to decipher and visualize disease-related RNA interactomes.

Your tasks:

• Combine the power of chemistry, biology, and physics with proteomic and metabolomic analysis;

• Use molecular biology, organic chemistry, biochemistry, and imaging techniques;

• Accurately record, carefully analyze and present experimental data;

• Drive your research project under the direct supervision of the principal investigator;

• Collaborate in projects with an interdisciplinary team of doctoral students and postdocs with different backgrounds and expertise;

• Engage in proposal writing and networking;

• Present your research at scientific forums.

Your profile:

• Master’s degree (for PhD position) or PhD degree (for PostDocs position) in organic chemistry, biochemistry, molecular biology, or any related field;

• Strong interest in RNA biotechnology, RNA biochemistry, microscopy, probes and method development;

• Experience in classical biochemical and molecular biology methods is an asset;

• Knowledge of biochemical and bioanalytical platforms for proteomics and next-generation sequencing is an advantage;

• Ability to work and collaborate in an interdisciplinary team;

• Proactive, independent, and solution-oriented way of working.

• Fluency in English in written and spoken language;

• Good presentation and writing skills;

 We offer:

• A clear research topic as well as multifold training and support;

• A stimulating international and interdisciplinary research environment;

• Integration into a research team that is committed to delivering the highest standards of research in a fair, supportive and collaborative manner;

• Research that contributes to advancing the frontiers of scientific knowledge;

• Excellent research facilities at IPMB (Heidelberg University) with access to state-of-the-art tools and infrastructure;

• The opportunity to present your data at national and international conferences and participate in workshops.

Application details:

The deadline for the application is February 15, 2024. The application package including

• Cover letter (2 page maximum) that clearly states

  • Your research and career interests

  • Any previous research experience (final year projects, internship(s), summer placement(s), year in industry, etc.)

  • Why you want to pursue a PhD or PostDoc and why you chose the Sunbul group

• Curriculum Vitae with contact details (phone and email) of two academic references

• Copies of your diplomas, bachelor and master grades (only for PhD applications)

should be submitted to [email protected] as a single pdf document (no more than 5 MB). For further information on the research group please visit: https://sunbulgroup.com

About Heidelberg University and the Institute of Pharmacy and Molecular Biotechnology:

Founded in 1386, Heidelberg University, a state university of Baden-Württemberg, is Germany’s oldest university. The Institute of Pharmacy and Molecular Biotechnology within the Faculty of Biosciences is focused on the development, investigation, and application of drugs and bioactive compounds, as well as on the elucidation of molecular and cellular mechanisms of action. This research integrates experimental approaches of chemistry, molecular and cellular biology, pharmacology, bioinformatics, and pharmaceutics. Main research areas of our institute include nucleic acids as tools and drug targets, development of new anti-infective drugs, molecular evolution & proteomics, research on neurodegenerative diseases, systems biology as well as drug targeting and transport.

Heidelberg University stands for equal opportunities and diversity. Qualified female candidates are especially invited to apply. Disabled persons will be given preference if they are equally qualified.

Requirements

Research Field

Chemistry » Biochemistry

Education Level

Master Degree or equivalent

Additional Information

Website for additional job details

https://sunbulgroup.com/

Work Location(s)

Number of offers available

1

Company/Institute

Heidelberg University

Country

Germany

Geofield

Where to apply

E-mail

[email protected]

Contact

State/Province

BW

City

Heidelberg

Website

https://www.ipmb.uni-heidelberg.de/index_en.html

Street

Im Neuenheimer Feld 364

Postal Code

69120

STATUS: EXPIRED