16 Jan 2024
Job Information
- Organisation/Company
TU Darmstadt- Department
Graduate School Life Science Engineering- Research Field
Biological sciences
Chemistry
Physics
Engineering- Researcher Profile
First Stage Researcher (R1)- Country
Germany- Application Deadline
29 Feb 2024 - 20:00 (Europe/Berlin)- Type of Contract
Temporary- Job Status
Full-time- Offer Starting Date
1 May 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Unlock Your Research Potential: Join the Graduate School LSE!
Embark on an exciting journey at the interface between engineering and life sciences with TU Darmstadt's Graduate School LSE. We are thrilled to announce a unique opportunity for international PhD students under the prestigious Graduate School Scholarship Programme (GSSP) of the German Academic Exchange Service (DAAD).
What We Offer:
- Interdisciplinary Research: Explore cutting-edge projects at the intersection of engineering and life sciences
- Global Network: Join a vibrant community of scientists and experts from diverse backgrounds.
- Excellence in Supervision: Conduct your doctoral studies under the supervision of renowned scientists and benefit from the accompanying PhD programme of the Graduate School LSE
For 2024, there is one scholarship available for doctoral studies to begin May – December 2024 (starting dates are dependent on the application and visa process) in one of the following research group:
Prof. Dr. Marco Durante, Radiation Biophysics : Brain tumors are among those most difficult to treat. In the PhD project, 3D assembloids, generated via fusion of tumor and brain organoids will be used to study the interaction of cancerous and non-cancerous cells in response to ionizing radiation. By identifying the cell types involved in the protection of cancer cells and its underlying mechanisms, countermeasures to shape the tumor microenvironment in a way that supports fighting brain tumors while protecting the normal tissue will be developed and tested.
Prof. Dr. Beatrix Suess, Synthetic RNAbiology : Based on our expertise in the selection of protein-binding RNA aptamers, we have designed a project for the development of RNA-based antibiotics in response to the growing antibiotics crisis. We will apply a targeted, in vitro selection method (SELEX) to develop RNA aptamers which can efficiently kill pathogenic bacteria.
Prof. Dr. Andreas Blaeser, BioMedical Printing Technology : 3D bioprinting is a biomedical key technology in which living cells embedded in a hydrogel matrix are printed in order to build up vital tissue. As part of the project, new 3D bioprinting techniques are being explored with the aim of creating vascularized tissue structures. These can be cultivated in bioreactors or in miniaturized form in organ-on-a-chip systems. Finally, the biofunctionality of the biofabricated organ-like precursors will be assessed using biochemical and pharmacological assays.
Prof. Dr. Alexander Loewer, System Biology of the Stress Response : The Loewer lab investigates signaling in individual living cells. In the available project, we aim to employ systems and synthetic biology approaches to identify design principles of molecular networks for information processing. To this end, we will combine genome engineering and live-cell microscopy with computational data analysis and modeling.
Prof. Dr. Nico Bruns, Sustainable Functional Polymers : Our bioengineering PhD project aims to craft artificial cells designed to establish effective relationships with natural cells, an idea with promising applications in healthcare and environmental science. The project focuses on fabricating synthetic structures equipped with bacterial elements to interact synergistically with living yeast and insect cells, potentially offering mutual benefits. Furthermore, the project will investigate incorporating elements from photosynthetic bacteria into these artificial cells, aiming to uncover innovative ways in which artificial and natural cellular systems can cooperate.
Prof. Dr. Felix Hausch, Structure-based drug research : We develop ‘smart’ drugs based on molecular proximity (molecular glues) using engineered biochemical or cellular systems in combination with modern organic synthesis to address otherwise untractable drug targets. In this PhD project, we will develop FKBP51-assisted molecular glues for Hsp90-dependent drug targets. This is based on our recent fundamental insights into the architecture of FKBP51-Hsp90-client complexes (Baischew, Engel, Nat Struct Mol Biol 2023) and our experience in molecular blues and proximity-based pharmacology (e.g. Geiger Angew Chem 2023 and Deutscher 10.26434/chemrxiv-2023-4vb0m).
Join us in pushing the boundaries of knowledge and fostering groundbreaking discoveries. Your journey to academic excellence starts here!
Requirements
- Research Field
- Biological sciences
- Education Level
- Master Degree or equivalent
- Research Field
- Chemistry
- Education Level
- Master Degree or equivalent
- Research Field
- Physics
- Education Level
- Master Degree or equivalent
- Research Field
- Engineering
- Education Level
- Master Degree or equivalent
Skills/Qualifications
Please carefully review the application requirements and admission process BEFORE submitting your application here .
Applications are exclusively accepted via the online application form .
- Languages
- ENGLISH
- Level
- Excellent
Additional Information
- Website for additional job details
https://www.tu-darmstadt.de/graduate-school-lse/phd_program/funding/daad_gssp/d…
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- TU Darmstadt
- Country
- Germany
- State/Province
- Hessen
- City
- Darmstadt
- Postal Code
- 64283
- Street
- Merckstraße 25
- Geofield
Where to apply
- Website
https://www.tu-darmstadt.de/graduate-school-lse/how_to_apply/application/online…
Contact
- State/Province
Hesse- City
Darmstadt- Website
https://www.tu-darmstadt.de/graduate-school-lse/phd_program/funding/daad_gssp/daad_gssp.en.jsp
https://www.tu-darmstadt.de/graduate-school-lse/about/about_the_graduate_school/index.en.jsp- Street
Merckstraße 25- Postal Code
64287
[email protected]
STATUS: EXPIRED